Porous scaffolds with the structure of an interpenetrating polymer network made by gelatin methacrylated nanoparticle-stabilized high internal phase emulsion polymerization targeted for tissue engineering
Atefeh Safaei-Yaraziz, Shiva Akbari‐Birgani, Nasser Nikfarjam
Abstract
= 74%, pH = 12, GeMA = 4 wt%, and GelMA/PEGDAC = 10/8. Then, PCL in different contents was infiltrated into the scaffold to balance hydrophilicity and hydrophobicity. The cell culture assay proved that the scaffold with a pore size of 60-180 μm and containing 51.2 wt% GelMA, 10.3 wt% PEG, and PCL 27.2 wt% provided a suitable microenvironment for mouse fibroblast cell (L929) adhesion, growth, and spreading. These results show that this strategy suggests promising culture for tissue engineering applications.
Topics & Concepts
GelatinInterpenetrating polymer networkEmulsion polymerizationPolymerizationPolymerMaterials scienceEmulsionNanoparticleChemical engineeringPorosityTissue engineeringPolymer chemistryComposite materialChemistryBiomedical engineeringNanotechnologyOrganic chemistryEngineeringMedicinePickering emulsions and particle stabilization3D Printing in Biomedical ResearchAdvanced Polymer Synthesis and Characterization