Merkel-cell carcinoma: ESMO–EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up
Iwona Ługowska, Jürgen C. Becker, Paolo A. Ascierto, Michael Veness, Astrid Blom, Célèste Lebbé, Emilia Migliano, Olga Hamming‐Vrieze, M. Goebeler, Hermann Kneitz, Paul Nathan, Piotr Rutkowski, Monika Słowińska, Dirk Schadendorf, Josep M. Piulats, Fausto Petrelli, Alexander C. J. van Akkooi, Alfredo Berruti
Abstract
•This ESMO Clinical Practice Guideline provides key recommendations for managing Merkel-cell carcinoma (MCC).•Recommendations are based on available scientific data and the multidisciplinary group of experts’ collective opinion.•The guideline covers clinical and pathological diagnosis, staging and risk assessment, treatment and follow-up.•Algorithms for the management of locoregional and inoperable/metastatic disease are provided.•A multidisciplinary team with a high level of expertise in MCC should diagnose and make decisions about therapy.