Risk factors for mortality, ICU admission and bacteremia in patients suspected of sepsis at the Emergency department. A prospective cohort study
Valentino D’Onofrio, Agnes Meersman, Sara Vijgen, Reinoud Cartuyvels, Peter Messiaen, Inge C. Gyssens
Abstract
BACKGROUND: There is a clear need for a better assessment of independent risk factors for in-hospital mortality, intensive care unit admission, and bacteremia in patients presenting with suspected sepsis at the emergency department. METHODS: A prospective observational cohort study including 1690 patients was performed. Two multivariable logistic regression models were used to identify independent risk factors. RESULTS: Sequential organ failure assessment (SOFA) score of ≥2 and serum lactate of ≥2mmol/L were associated with all outcomes. Other independent risk factors were individual SOFA variables and systemic inflammatory response syndrome variables but varied per outcome. Mean arterial pressure <70 mmHg negatively impacted all outcomes. CONCLUSIONS: These readily available measurements can help with early risk stratification and prediction of prognosis.