Litcius/Paper detail

Zn(II)-Stabilized Azo-Anion Radical-Catalyzed Dehydrogenative Synthesis of Olefins

Subhasree Pal, Amit Kumar Guin, Subhankar Khanra, Nanda D. Paul

2024The Journal of Organic Chemistry11 citationsDOI

Abstract

Herein, we describe a Zn-catalyzed atom-economical, inexpensive, and sustainable method for preparing a broad spectrum of substituted olefins utilizing alcohols as the main precursor. Using a Zn(II) complex [ZnLCl 2 ] ( 1 ) of the redox-noninnocent ligand 2-((4-chlorophenyl)diazenyl)-1,10-phenanthroline ( L ), various ( E )-olefins were prepared in good yields by coupling alcohols with sulfones and aryl cyanides under an inert atmosphere. Under an aerial atmosphere, vinyl nitriles were isolated in up to 82% yield reacting alcohols with benzyl cyanides in the presence of 1 . Control experiments and mechanistic investigation indicate the active involvement of the aryl-azo ligand as an electron and hydrogen reservoir, permitting 1 to perform as a promising catalyst.

Topics & Concepts

CatalysisChemistryArylLigand (biochemistry)Yield (engineering)Inert gasRedoxRadicalOrganic chemistryMaterials scienceAlkylMetallurgyReceptorBiochemistryAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions