New neuroprotective derivatives of cinnamic acid by biotransformation
Hadeer Elkharsawy, Ramadan A. El-Domany, Amira Mira, Amal F. Soliman, Mohamed Sabry, Saleh El-Sharkawy
Abstract
induced-neurotoxicity than catechin and epigallocatechin-3-gallate as positive controls. This study suggested the two new metabolites 2̲ and 3̲ along with metabolite 4̲ as potential leads for neurodegenerative diseases associated with cholinergic deficiency, neurotoxicity or neuroinflammation.
Topics & Concepts
BiotransformationNeuroprotectionCinnamic acidChemistryPharmacologyBiochemistryMedicineEnzymeNatural Antidiabetic Agents StudiesBiochemical Acid Research StudiesCholinesterase and Neurodegenerative Diseases