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Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice

Pan Su, Mengdi Wu, Xiaoting Yin, Mengyuan Li, Yucheng Li, Ming Bai, Baoying Wang, Erping Xu

2023Journal of Ethnopharmacology39 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayAutophagyMicrogliaProtein kinase BLipopolysaccharideChemistryMedicineCell biologyBiologySignal transductionImmunologyInflammationApoptosisBiochemistryTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancer
Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice | Litcius