Unified Approach to Imidodiphosphate-Type Brønsted Acids with Tunable Confinement and Acidity
Sebastian Schwengers, Chandra Kanta De, Oleg Grossmann, Joyce A. A. Grimm, Natascha R. Sadlowski, Gabriela G. Gerosa, Benjamin List
Abstract
-propyl sulfide. Furthermore, the methodology delivers a novel, rationally designed super acidic catalyst motif, imidodiphosphorbis(iminosulfonylimino)imidate (IDPii), the extreme reactivity of which exceeds commonly employed super-Brønsted acids, such as trifluoromethanesulfonic acid. The unique reactivity of one such IDPii catalyst has been demonstrated in the first α-methylation of a silyl ketene acetal with methanol as the electrophilic alkylating reagent.
Topics & Concepts
ChemistryCatalysisKeteneReagentBrønsted–Lowry acid–base theoryElectrophileReactivity (psychology)Combinatorial chemistryChlorideSulfideMethanolMethylationSilylationAcetalOrganic chemistryMedicinePathologyAlternative medicineGeneBiochemistrySynthesis and Catalytic ReactionsAsymmetric Synthesis and CatalysisSynthetic Organic Chemistry Methods