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Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics

Yue Sun, Sze Yi Lau, Zhi Wei Lim, Shi Chieh Chang, Farid J. Ghadessy, Anthony W. Partridge, Ali Miserez

2022Nature Chemistry383 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryCoacervateIntracellularCytosolEndosomeMacromoleculeDrug deliveryBiophysicsCell biologyBiochemistryEnzymeBiologyOrganic chemistryRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesExtracellular vesicles in disease
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