A reactive oxygen species-responsive covalent organic framework for tumor combination therapy
Wenyan Li, Jing‐Lan Kan, Jing-Jing Wan, Yanan Li, Tian Song, Bo Wang, Qun Guan, Lele Zhou, Yu‐Bin Dong
Abstract
Herein, we report the first reactive oxygen species (ROS)-responsive dithioketal-linked covalent organic framework (COF) for synergetic chemotherapy and photodynamic therapy (PDT) of cancer.
Topics & Concepts
Singlet oxygenPhotodynamic therapyReactive oxygen speciesCovalent bondDissociation (chemistry)Cancer therapyChemistryOxygenCombinatorial chemistryPhotochemistryCancerOrganic chemistryBiochemistryMedicineInternal medicineCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and ApplicationsNanoplatforms for cancer theranostics