Aromadendrin: a dual amyloid promoter to accelerate fibrillization and reduce cytotoxicity of both amyloid-β and hIAPP
Yanxian Zhang, Dong Zhang, Yijing Tang, Baiping Ren, Fufeng Liu, Lijian Xu, Yung Chang, Jie Zheng
Abstract
Aromadendrin, as a protective amyloid promoter, is discovered to simultaneously promote the aggregation of Aβ and hIAPP peptides and reduce the amyloid-induced cytotoxicity.
Topics & Concepts
CytotoxicityAmyloid (mycology)ChemistryAmyloid βDual (grammatical number)PeptideBiochemistryBiophysicsBiologyIn vitroMedicineInternal medicineArtDiseaseLiteratureInorganic chemistryAlzheimer's disease research and treatmentsDrug Transport and Resistance MechanismsAmyloidosis: Diagnosis, Treatment, Outcomes