The Use of Artificial Intelligence for Cancer Therapeutic Decision-Making
Olivier Elemento, Sean Khozin, Cora N. Sternberg
Abstract
Artificial intelligence (AI) has the potential to transform cancer therapeutic decision-making by improving diagnostics and personalizing treatments. This review explores the current and future impact of AI in oncology, focusing on its applications in radiology, pathology, and the potential of Large Language Models (LLMs) in treatment selection. Despite significant advancements, AI integration into clinical workflows is limited due to challenges like data quality, model accuracy, and lack of validation through clinical trials. We propose key strategies to address these challenges, including developing robust multi-center datasets, promoting practical AI model development, researching workflow integration and human-AI collaboration, leveraging lessons from AI in medical imaging, establishing evaluation guidelines, and incentivizing prospective clinical trials. By implementing these strategies, AI can significantly enhance cancer care and patient outcomes, paving the way for its effective integration into oncology practice.