The Novel GlycoPEGylated FGF21 Analog Pegozafermin Activates Human FGF Receptors and Improves Metabolic and Liver Outcomes in Diabetic Monkeys and Healthy Human Volunteers
Moti Rosenstock, Leo Tseng, Andrew L. Pierce, Elliot Offman, Chaoyin Chen, R. Will Charlton, Maya Margalit, Hank Mansbach
Topics & Concepts
FGF21EndocrinologyInternal medicineAdiponectinMedicineHypertriglyceridemiaSteatohepatitisGlycated hemoglobinLipid metabolismGlucose homeostasisDiabetes mellitusInsulin resistanceFatty liverTriglycerideReceptorCholesterolFibroblast growth factorType 2 diabetesDiseaseFibroblast Growth Factor ResearchEpigenetics and DNA MethylationKruppel-like factors research