Randomised, Phase II study of selumetinib, an oral inhibitor of MEK, in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer
Mark Doherty, Vincent C. Tam, Mairéad G. McNamara, Raymond Woo-Jun Jang, David W. Hedley, Eric X. Chen, Neesha C. Dhani, Patricia A. Tang, Hao‐Wen Sim, Grainne M. O’Kane, Stephanie DeLuca, Lisa Wang, Theresa Pedutem, Jennifer J. Knox
Topics & Concepts
SelumetinibGemcitabineMedicineChemotherapyMEK inhibitorCisplatinInternal medicineToxicityOncologyUrologyGastroenterologySurgeryCancerMAPK/ERK pathwayBiologyKinaseColorectal cancerCell biologyKRASCholangiocarcinoma and Gallbladder Cancer StudiesLiver physiology and pathologyGallbladder and Bile Duct Disorders