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Haplotype-aware analysis of somatic copy number variations from single-cell transcriptomes

Teng Gao, Ruslan Soldatov, Hirak Sarkar, Adam Kurkiewicz, Evan Biederstedt, Po‐Ru Loh, Peter V. Kharchenko

2022Nature Biotechnology169 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCopy-number variationHaplotypeCopy number analysisGeneticsGenotypingComputational biologyGenomeTranscriptomeSomatic cellPopulationAlleleGeneGenotypeGene expressionDemographySociologyCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsEvolution and Genetic Dynamics
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