Synthesis, characterization, molecular docking, RNA-sequence and anticancer efficacy evaluation in vitro of ruthenium(II) complexes on B16 cells
Chunxia Huang, Huiwen Zhang, Yan Yang, Haimei Liu, Jing Chen, Yi Wang, Lijuan Liang, Huiyan Hu, Yunjun Liu
Topics & Concepts
ChemistryApoptosisAnnexinRutheniumCytotoxicityIn vitroReactive oxygen speciesIntracellularMitochondrial permeability transition porePhenanthrolineBromideMTT assayStereochemistryMolecular biologyBiochemistryProgrammed cell deathCrystallographyBiologyOrganic chemistryCatalysisMetal complexes synthesis and propertiesSynthesis of Tetrazole DerivativesSynthesis and Characterization of Heterocyclic Compounds