Competition Sensing Changes Antibiotic Production in <i>Streptomyces</i>
Sanne Westhoff, Alexander Kloosterman, Stephan F. A. van Hoesel, Gilles P. van Wezel, Daniel E. Rozen
Abstract
cells also often reduce their output of antibiotics when grown with competitors, especially under nutrient limitation. Our findings highlight that interactions between the social and resource environments strongly regulate antibiotic production in these medicinally important bacteria.
Topics & Concepts
AntibioticsBacteriaCompetition (biology)Competitor analysisStreptomycesMicrobiologyProduction (economics)Antibiotic resistanceBiologyBiotechnologyBusinessEcologyMarketingEconomicsGeneticsMacroeconomicsMicrobial Natural Products and BiosynthesisChemical synthesis and alkaloidsAlkaloids: synthesis and pharmacology