Litcius/Paper detail

The spatial multi-omics revolution in cancer therapy: Precision redefined

Yanhua Du, Xinyu Ding, Youqiong Ye

2024Cell Reports Medicine37 citationsDOIOpen Access PDF

Abstract

Spatially resolved multi-omics revolutionizes cancer therapy by decoding the cellular and molecular heterogeneity of the tumor microenvironment through spatial coordinates. This commentary discusses the roles of spatial multi-omics in identifying precise therapeutic targets and predicting treatment responses while also highlighting the challenges that impede its integration into precision medicine. Spatially resolved multi-omics revolutionizes cancer therapy by decoding the cellular and molecular heterogeneity of the tumor microenvironment through spatial coordinates. This commentary discusses the roles of spatial multi-omics in identifying precise therapeutic targets and predicting treatment responses while also highlighting the challenges that impede its integration into precision medicine.

Topics & Concepts

OmicsCancer therapyCancerComputational biologyComputer scienceData scienceBiologyBioinformaticsGeneticsCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsEpigenetics and DNA Methylation