Increased Hydrostatic Pressure Promotes Primary M1 Reaction and Secondary M2 Polarization in Macrophages
Bo Wang, Maren Kasper, Björn Laffer, Gerd Meyer zu Hörste, Susanne Wasmuth, Martin Busch, Tida Viola Jalilvand, Solon Thanos, Arnd Heiligenhaus, Dirk Bauer, Carsten Heinz
Abstract
= 0.0454). These changes in the M1/M2 phenotype by high HP or Dex treatment may play a role in the pathogenesis of secondary uveitic glaucoma- or glucocorticoid (GC)-induced glaucoma.
Topics & Concepts
Hydrostatic pressureM2 MacrophageCD86Macrophage polarizationPhenotypeLipopolysaccharideCD163DexamethasoneUveitisMacrophageTumor necrosis factor alphaChemistryMolecular biologyImmunologyMedicineEndocrinologyIn vitroBiologyBiochemistryGenePhysicsThermodynamicsGlaucoma and retinal disordersImmune Response and InflammationImmune cells in cancer