Prediction of hepatic drug clearance with a human microfluidic four-cell liver acinus microphysiology system
Courtney Sakolish, Yu‐Syuan Luo, Alan Valdiviezo, Lawrence A. Vernetti, Ivan Rusyn, Weihsueh A. Chiu
Topics & Concepts
In vivoHepatocyteHepatic stellate cellInduced pluripotent stem cellCell cultureAcinusPharmacologyBiologyIn vitroIn vitro toxicologyChemistryEndocrinologyBiochemistryEmbryonic stem cellGeneticsPancreasBiotechnologyGenePharmacogenetics and Drug Metabolism3D Printing in Biomedical ResearchStatistical Methods in Clinical Trials