Litcius/Paper detail

Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme

Jingfang Song, Jian He, Lin Yang, Weiguo Wang, Qinqin Bai, Feng Wei, Ranhui Li

2023Bioinorganic Chemistry and Applications17 citationsDOIOpen Access PDF

Abstract

To inhibit the growth of bacteria, the DA-PPI nanozyme with enhanced peroxidase-like activity was synthesized. The DA-PPI nanozyme was obtained by depositing high-affinity element iridium (Ir) on the surface of Pd-Pt dendritic structures. The morphology and composition of DA-PPI nanozyme were characterized using SEM, TEM, and XPS. The kinetic results showed that the DA-PPI nanozyme possessed a higher peroxidase-like activity than that of Pd-Pt dendritic structures. The PL, ESR, and DFT were employed to explain the high peroxidase activity. As a proof of concept, the DA-PPI nanozyme could effectively inhibit E. coli (G−) and S. aureus (G+) due to its high peroxidase-like activity. The study provides a new idea for the design of high active nanozymes and their application in the field of antibacterial.

Topics & Concepts

ChemistryPeroxidaseAntibacterial activityCombinatorial chemistryX-ray photoelectron spectroscopyBacteriaNuclear chemistryEnzymeNanotechnologyBiochemistryChemical engineeringMaterials scienceBiologyEngineeringGeneticsAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniques