Endothelial HMGB1-AIM2 axis worsens myocardial ischemia—reperfusion injury by regulating endothelial pyroptosis
Rui Chen, Junying Duan, Zhou Ye, Mengfei Cao, Ye Su, Duzhe Jiang, Aibin Tao, Wei Yuan, Zhiying Dai
Topics & Concepts
PyroptosisHMGB1Reperfusion injuryIschemiaMyocardial ischemiaMedicineCell biologyApoptosisCardiologyInflammationInternal medicineChemistryBiologyInflammasomeBiochemistryAdvanced Glycation End Products researchNeutrophil, Myeloperoxidase and Oxidative MechanismsInflammasome and immune disorders