Package delivered: folate receptor-mediated transporters in cancer therapy and diagnosis
Mohsen Ahmadi, Christoph A. Ritter, Thomas von Woedtke, Sander Bekeschus, Kristian Wende
Abstract
s and to facilitate the understanding of the relevant chemistry and biochemical pathways. Focusing exemplarily on brain and breast cancer, recent advances spanning 2017 to 2023 in conjugated nanocarriers and small molecule drug conjugates were considered, evaluating the chemical and biological aspects in order to improve accessibility to the field and to bridge chemical and biomedical points of view ultimately guiding future research in FR-targeted cancer therapy and diagnosis.
Topics & Concepts
Folate receptorTransporterCancer therapyCancer researchReceptorComputational biologyMedicineCancerChemistryBiologyInternal medicineCancer cellBiochemistryGeneNanoparticle-Based Drug DeliveryFolate and B Vitamins ResearchGraphene and Nanomaterials Applications