Photoinduced efficient synthesis of cyanoalkylsulfonylated oxindoles <i>via</i> sulfur dioxide insertion
Fan Teng, Juan Du, Changping Xun, Mengxue Zhu, Ziqin Lu, Hongmei Jiang, Yu‐Ling Chen, Li Yu, Qingwen Gui
Abstract
-arylacrylamide and cyclobutanone oxime esters with sulfur dioxide insertion is established. Mainly through the exploration of the visible light wavelength, it is found that the light source has a certain influence on the formation of cyanoalkylsulfonylated oxindoles, furnishing a range of sulfones in good to excellent yields. This protocol presents good functional group compatibility and does not require transition metals, photosensitizers, external bases, or oxidants.
Topics & Concepts
ChemistryCyclobutanoneVisible spectrumSulfur dioxideSulfurFunctional groupCascadePhotochemistryCombinatorial chemistryOximeOrganic chemistryOptoelectronicsPolymerPhysicsRing (chemistry)ChromatographySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsChemical Synthesis and Reactions