Synthesis, Biological, and Molecular Docking Studies on 4,5,6,7-Tetrahydrobenzo[<i>b</i>]thiophene Derivatives and Their Nanoparticles Targeting Colorectal Cancer
Shimaa Kamal, Hamed A. Derbala, Seham S. Alterary, Abir Ben Bacha, Mona Alonazi, Mohamed K. El‐Ashrey, Nahed N. E. El-Sayed
Abstract
to the protein; in addition, the absorption, distribution, metabolism, and excretion (ADME) analyses showed its desirable drug-likeness and oral bioavailability characteristics.
Topics & Concepts
ChemistryIC50Colorectal cancerDocking (animal)AntioxidantCytotoxicityBiochemistryCytotoxic T cellPharmacologyCancerIn vitroBiologyMedicineGeneticsNursingSynthesis and biological activityEnzyme function and inhibitionSynthesis and Characterization of Heterocyclic Compounds