Targeting LEF1-mediated epithelial-mesenchymal transition reverses lenvatinib resistance in hepatocellular carcinoma
Xinxiu Li, Hongmeng Su, Wenqing Tang, Shihui Shu, Luyu Zhao, Jinghan Sun, Hong Fan
Topics & Concepts
LenvatinibCancer researchWnt signaling pathwayEpithelial–mesenchymal transitionHepatocellular carcinomaDownregulation and upregulationMedicineOncologyBiologySignal transductionGeneSorafenibCell biologyGeneticsCancer Mechanisms and TherapyLiver physiology and pathologyCancer-related gene regulation