Litcius/Paper detail

Using Genomic Selection to Leverage Resources among Breeding Programs: Consortium-Based Breeding

Clay Sneller, John Carlos I. Ignacio, Brian Ward, Jessica Rutkoski, Mohsen Mohammadi

2021Agronomy19 citationsDOIOpen Access PDF

Abstract

Genomic selection has many applications within individual programs. Here, we discuss the benefits of forming a GS-based breeding consortium (GSC) among programs within the context of a recently formed a GSC of soft red winter wheat breeding programs. The GSC will genotype lines from each member breeding program (MBP) and conduct cooperative phenotyping. The primary GSC benefit is that each MBP can use GS to predict the local and broad value of all germplasm from all MBPs including lines in the early stages of testing, thus increasing the effective size of each MBP without significant new investment. We identified eight breeding aspects that are essential to GSC success and analyzed how our GSC fits those criteria. We identified a core of >5700 related lines from the MBPs that can serve in training populations. Germplasm from each MBP provided breeding value to other MBPs and program-specific adaption was low. GS accuracy was acceptable within programs but was low between programs when using training populations with little testing connectivity, but increased when using data from trials with high testing connectivity between MBPs. In response we initiated sparse-testing with a germplasm sharing scheme utilizing family relationship to connect our phenotyping of early-stage lines.

Topics & Concepts

GermplasmBreeding programLeverage (statistics)Genomic selectionSelection (genetic algorithm)BiologyContext (archaeology)BiotechnologyGenetic gainComputer scienceGenotypeGeneticsCultivarGenetic variationAgronomyArtificial intelligencePaleontologySingle-nucleotide polymorphismGeneGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and AnimalsWheat and Barley Genetics and Pathology