OCRL regulates lysosome positioning and mTORC1 activity through SSX2IP-mediated microtubule anchoring
Biao Wang, Wei He, Philipp P. Prosseda, Liang Li, Tia J. Kowal, Jorge A. Alvarado, Qing Wang, Yang Hu, Yang Sun
Topics & Concepts
LysosomemTORC1Cell biologyAnchoringMicrotubuleBiologyBiochemistrySignal transductionPsychologyPI3K/AKT/mTOR pathwayEnzymeCognitive scienceCellular transport and secretionMicrotubule and mitosis dynamicsGenetic and Kidney Cyst Diseases