Immune regulation based on sex differences in ischemic stroke pathology
Pingping Niu, Liqin Li, Yonggang Zhang, Zhongzhou Su, Binghao Wang, He Liu, Shehong Zhang, Sheng Qiu, Yuntao Li
Abstract
Ischemic stroke is one of the world's leading causes of death and disability. It has been established that gender differences in stroke outcomes prevail, and the immune response after stroke is an important factor affecting patient outcomes. However, gender disparities lead to different immune metabolic tendencies closely related to immune regulation after stroke. The present review provides a comprehensive overview of the role and mechanism of immune regulation based on sex differences in ischemic stroke pathology.
Topics & Concepts
Stroke (engine)Immune systemMedicineMechanism (biology)Ischemic strokeImmunologyBioinformaticsInternal medicineIschemiaBiologyEngineeringMechanical engineeringEpistemologyPhilosophyNeuroinflammation and Neurodegeneration MechanismsAtherosclerosis and Cardiovascular DiseasesImmune cells in cancer