<i>Porphyromonas Gingivalis</i> in the Development of Periodontitis: Impact on Dysbiosis and Inflammation.
Asma Gasmi Benahmed, Pavan Kumar Mujawdiya, Sàdaf Noor, Amin Gasmi
Abstract
. Its presence in the periodontal tissues increases the secretion of numerous pro-inflammatory mediators such as TNF-α, IL-8, and IL-1β, leading to the destruction of soft gingival tissues and ligaments. Early detection of periodontitis and immediate treatment can prevent soft tissue destruction and dentition loss. In conclusion, details about the oral microbiome, oral dysbiosis, and inflammation may offer new therapeutic options in the future, including a personalized approach and the use of combination therapy.
Topics & Concepts
Porphyromonas gingivalisPeriodontitisDysbiosisMicrobiologyFusobacterium nucleatumMedicineAggregatibacter actinomycetemcomitansImmunologyBiologyDentistryGut floraOral microbiology and periodontitis researchOral Health Pathology and TreatmentEndodontics and Root Canal Treatments