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A Bird's‐Eye View on Deep Eutectic Solvent‐Mediated Multicomponent Synthesis of <i>N</i> ‐Heterocycles

Lokesh Kumar S, Anushka Servesh, Yash Kumar Sriwastav, Sanjaybala Balasubramanian, Sumaiya Tabassum, Santhosh Govindaraju

2023ChemistrySelect25 citationsDOI

Abstract

Abstract Multicomponent reactions are crucial for operating organic synthesis. In today's world, chemists concentrate on greener methodologies that cater to rising environmental concerns. Most conventional organic solvents are harsh on the environment, which can be addressed by environmentally and pocket‐friendly Deep eutectic solvents (DES). Organic synthesis via MCR in the presence of DES has resulted in the blend of green methodology and green solvent for organic transformations. Forasmuch as addressing the environmental concerns and developing higher heterocycles, our review focuses on the literature published on the DES‐mediated Multicomponent synthesis of N ‐Heterocyclic compounds.

Topics & Concepts

Environmentally friendlyOrganic synthesisEutectic systemDeep eutectic solventGreen chemistryOrganic solventSolventOrganic chemistryChemistryBiochemical engineeringCombinatorial chemistryEnvironmental scienceNanotechnologyEnvironmental chemistryChemical engineeringMaterials scienceEngineeringCatalysisReaction mechanismEcologyAlloyBiologyMulticomponent Synthesis of HeterocyclesSynthesis and Biological EvaluationChemical Synthesis and Reactions