Rho/SMAD/mTOR triple inhibition enables long-term expansion of human neonatal tracheal aspirate-derived airway basal cell-like cells
Junjie Lu, Xiaobo Zhu, Jessica E. Shui, Linjie Xiong, Todd M. Gierahn, Cheng Zhang, Michael A. Wood, Suzanne Hally, J. Christopher Love, Hu Li, Benjamin C. Crawford, Hongmei Mou, Paul H. Lerou
Topics & Concepts
PI3K/AKT/mTOR pathwayBiologyRespiratory epitheliumBronchopulmonary dysplasiaCell biologyEpitheliumCancer researchProgenitor cellPathologySMADMedicineStem cellSignal transductionGeneticsGestational agePregnancyNeonatal Respiratory Health ResearchTracheal and airway disordersCongenital Diaphragmatic Hernia Studies