Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells
Yujuan Zhan, Qiugu Chen, Yue Song, Xianli Wei, Tingxiu Zhao, Bonan Chen, Chengxi Li, Wenbo Zhang, Yanjun Jiang, Yuhui Tan, Biaoyan Du, Jianyong Xiao, Kun Wang
Topics & Concepts
ApoptosisReactive oxygen speciesAutophagyCathepsin BCancer cellCancer researchCisplatinCathepsin DProgrammed cell deathBiologyChemistryPharmacologyCell biologyCancerBiochemistryChemotherapyEnzymeGeneticsAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolismSphingolipid Metabolism and Signaling