Injectable hydrogel enables local and sustained co-delivery to the brain: Two clinically approved biomolecules, cyclosporine and erythropoietin, accelerate functional recovery in rat model of stroke
Anup Tuladhar, Jaclyn M. Obermeyer, Samantha L. Payne, Ricky Siu, Sohrab Zand, Cindi M. Morshead, Molly S. Shoichet
Topics & Concepts
ErythropoietinStroke (engine)Context (archaeology)Drug deliveryMedicineSystemic administrationPharmacologyProgenitor cellBlood–brain barrierStroke recoveryStriatumNeural stem cellNeuroscienceStem cellIn vivoCentral nervous systemInternal medicineMaterials scienceBiologyNanotechnologyBiotechnologyMechanical engineeringEngineeringGeneticsPhysical therapyPaleontologyRehabilitationDopamineNerve injury and regenerationNeurogenesis and neuroplasticity mechanismsPharmacological Effects and Toxicity Studies