Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer’s disease
Xueyang Jiang, Yang Wang, Chang Liu, Caiyi Xing, Yingming Wang, Weiping Lyu, Saisai Wang, Qihang Li, Tingkai Chen, Yao Chen, Feng Feng, Wenyuan Liu, Haopeng Sun
Topics & Concepts
NeuroprotectionGSK-3ChemistryCholinesterasePharmacologyGlycogen synthaseIC50BiochemistryIn vitroTacrineEnzymeKinaseAcetylcholinesteraseBiologyCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsNicotinic Acetylcholine Receptors Study