Practical scale up synthesis of carboxylic acids and their bioisosteres 5-substituted-1<i>H</i>-tetrazoles catalyzed by a graphene oxide-based solid acid carbocatalyst
R. Mittal, Amit Kumar, Satish Kumar Awasthi
Abstract
-tetrazoles was corroborated by single crystal X-ray analysis and computational calculations of the proposed reaction mechanism which correlated well with experimental findings. Both of the reactions could be performed efficiently at gram scale (10 g) using the SA-rGO catalyst. SA-rGO displays eminent reusability up to eight runs without significant decrease in its productivity. Thus, these features make SA-rGO riveting from an industrial perspective.
Topics & Concepts
CatalysisGrapheneOxideChemistryReusabilityCarboxylic acidSulfonic acidCombinatorial chemistryOrganic chemistryMaterials scienceNanotechnologySoftwareComputer scienceProgramming languageSynthesis of Tetrazole DerivativesMulticomponent Synthesis of HeterocyclesNanomaterials for catalytic reactions