Ambiphilic singlet carbenes: Electron donors and acceptors
Hyunho Kim, Eunsung Lee
Abstract
Abstract The isolation of cyclic(alkyl)(amino)carbenes (CAACs) and N , N ′‐diamidocarbenes (DACs) has opened up new avenues in the field of carbene chemistry due to their unique properties. CAACs are strong σ‐donors and π‐acceptors, whereas DACs are extremely strong π‐acceptors. The ambiphilicity of carbenes can facilitate new applications such as small molecule activation and catalysis. Since the isolation of CAACs and DACs, several new ambiphilic carbenes have been synthesized, thereby advancing the development of carbene chemistry. This review summarizes the most relevant findings on ambiphilic carbene chemistry until 2022.
Topics & Concepts
CarbeneChemistrySinglet stateCombinatorial chemistryIsolation (microbiology)PhotochemistryCatalysisComputational chemistryNanotechnologyOrganic chemistryMaterials sciencePhysicsMicrobiologyExcited stateBiologyNuclear physicsN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsCyclopropane Reaction Mechanisms