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Understanding Unreported Cases in the COVID-19 Epidemic Outbreak in Wuhan, China, and the Importance of Major Public Health Interventions

Zhihua Liu, Pierre Magal, Ousmane Seydi, Glenn F. Webb

2020Biology248 citationsDOIOpen Access PDF

Abstract

We develop a mathematical model to provide epidemic predictions for the COVID-19 epidemic in Wuhan, China. We use reported case data up to 31 January 2020 from the Chinese Center for Disease Control and Prevention and the Wuhan Municipal Health Commission to parameterize the model. From the parameterized model, we identify the number of unreported cases. We then use the model to project the epidemic forward with varying levels of public health interventions. The model predictions emphasize the importance of major public health interventions in controlling COVID-19 epidemics.

Topics & Concepts

OutbreakChinaPublic health interventionsPublic healthCoronavirus disease 2019 (COVID-19)Psychological interventionBiology2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Environmental healthVirologyDiseaseInfectious disease (medical specialty)Political scienceMedicineNursingPsychiatryPathologyLawCOVID-19 epidemiological studiesMathematical and Theoretical Epidemiology and Ecology ModelsCOVID-19 Pandemic Impacts
Understanding Unreported Cases in the COVID-19 Epidemic Outbreak in Wuhan, China, and the Importance of Major Public Health Interventions | Litcius