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Synthesis of Molecular Phenylcalcium Derivatives: Application to the Formation of Biaryls

Kyle G. Pearce, Chiara Dinoi, Michael S. Hill, Mary F. Mahon, Laurent Maron, Ryan J. Schwamm, Andrew S. S. Wilson

2022Angewandte Chemie International Edition18 citationsDOIOpen Access PDF

Abstract

Abstract Hydrocarbon‐soluble β‐diketiminato phenylcalcium derivatives, which display various modes of Ca−μ 2 ‐Ph−Ca bridging, are accessible from reactions of Ph 2 Hg and [(BDI)CaH] 2 . Although the resultant compounds are inert toward the C−H bonds of benzene, they yield selective and uncatalyzed biaryl formation when reacted with readily available aryl bromides.

Topics & Concepts

ChemistryBenzeneArylYield (engineering)Benzene derivativesInertOrganic chemistryHydrocarbonCatalysisCombinatorial chemistryChemical synthesisAlkylBiochemistryMetallurgyMaterials scienceIn vitroCoordination Chemistry and OrganometallicsCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions
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