A theoretical study of asymmetric ketone hydrogenation catalyzed by Mn complexes: from the catalytic mechanism to the catalyst design
Yaqi Zhao, Lin Zhang, Yanhui Tang, Min Pu, Ming Lei
Abstract
) were further designed and showed very good stereoselectivity, which is due to the lower deformation energy and stronger interactions between the ketone substrates and catalysts. This work may shed light on the design of cheap metal catalysts with a new ligand framework for the asymmetric hydrogenation (AH) of CX bonds (X = O, N).
Topics & Concepts
StereoselectivityCatalysisChemistryKetonePincer movementLigand (biochemistry)StereochemistryMedicinal chemistryOrganic chemistryReceptorBiochemistryAsymmetric Hydrogenation and CatalysisCatalysis for Biomass ConversionCarbon dioxide utilization in catalysis