CRISPR-based VEGF suppression using paired guide RNAs for treatment of choroidal neovascularization
Sook Hyun Chung, Tzu-Ni Sin, Brian Quang Dang, Taylor Ngo, Therlinder Lo, Daniella Lent-Schochet, Ratheesh K. Meleppat, Robert J. Zawadzki, Glenn Yiu
Abstract
gene as treatment for neovascular retinal conditions is unclear.
Topics & Concepts
CRISPRBiologyGuide RNAGenome editingCas9GeneticsComputational biologyTrans-activating crRNAGeneCRISPR and Genetic EngineeringRetinal Development and DisordersRNA Interference and Gene Delivery