Mechanochemical Direct Fluorination of Unactivated C(<i>sp</i><sup>3</sup>)−H Bonds
Sehye Min, Beomsoon Park, Jantakan Nedsaengtip, Soon Hyeok Hong
Abstract
Abstract The mechanochemical fluorination of unactivated C( sp 3 )−H bonds has been achieved using N ‐fluorobenzenesulfonimide as both a precursor of the hydrogen‐atom‐transfer reagent and a bench‐stable fluorine source. The control experiments revealed that mechanical energy is essential for realizing this reaction. magnified image
Topics & Concepts
ChemistryFluorineReagentHydrogen bondHydrogen atomAtom (system on chip)Organic chemistryMoleculeGroup (periodic table)Embedded systemComputer scienceFluorine in Organic ChemistryCrystallography and molecular interactionsSynthesis and Catalytic Reactions