The role of protein folding in prenucleation clusters on the activity of enzyme@metal–organic frameworks
Brooke P. Carpenter, Ben Rose, Elisa M. Olivas, Mariana X. Navarro, A. Rain Talosig, Paul J. Hurst, Giuseppe Di Palma, Lei Xing, Rweetuparna Guha, Stacy M. Copp, Joseph P. Patterson
Abstract
Two steps must be satisfied to achieve high activity enzyme@MOFs: proper enzyme folding and low MOF crystallinity.
Topics & Concepts
CrystallinityFolding (DSP implementation)EnzymeProtein foldingMetal-organic frameworkChemistryMaterials scienceCrystallographyBiochemistryOrganic chemistryEngineeringElectrical engineeringAdsorptionMetal-Organic Frameworks: Synthesis and ApplicationsDrug Transport and Resistance MechanismsMetal complexes synthesis and properties