Neoadjuvant immunotherapy: new horizon for lymph node preservation
Nian‐Nian Zhong, Bing Liu, Lin‐Lin Bu
Abstract
The study by Rahim et al., focusing on preoperative immunotherapy, highlights the pivotal role of CD8+ T cells within lymph nodes in response to neoadjuvant immunotherapy, suggesting that preserving lymph node integrity could bolster the treatment's efficacy by activating antitumor T cells. This underlines the importance of lymph node preservation and supports the use of immunotherapy as a neoadjuvant approach in cancer treatment.
Topics & Concepts
ImmunotherapyLymph nodeMedicineCD8Cancer researchHead and neck squamous-cell carcinomaLymphImmune systemT cellImmunologyOncologyCancerPathologyInternal medicineHead and neck cancerCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesBrain Metastases and Treatment