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Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial

Tracy J. Ruckwardt, Kaitlyn M. Morabito, Emily Phung, Michelle C. Crank, Pamela Costner, LaSonji A. Holman, Lauren A. Chang, Somia P. Hickman, Nina M. Berkowitz, Ingelise J. Gordon, Galina V. Yamshchikov, Martin R. Gaudinski, Bob C. Lin, Robert T. Bailer, Man Chen, Ana M. Ortega‐Villa, Thuy Nguyen, Azad Kumar, Richard Schwartz, Lisa A. Kueltzo, Judith A. Stein, Kevin Carlton, Jason G. Gall, Martha Nason, John R. Mascola, Grace Chen, Barney S. Graham, Anita Arthur, Jennifer Cunningham, Aba Mensima Eshun, Brenda Larkin, Floreliz Mendoza, Laura Novik, Jamie Saunders, Xiaolin Wang, William Whalen, Cristina Carter, Cynthia S. Hendel, Sarah H. Plummer, Abidemi Ola, Alicia T. Widge, Maria Claudia Burgos Florez, Lam Le, Iris Pittman, Ro Shauna Rothwell, Olga Trofymenko, Olga Vasilenko, Preeti Apte, Renunda Hicks, Cora Trelles Cartagena, Pernell Williams, LaShawn Requilman, Colin Tran, Shufeng Bai, Elizabeth J. Carey, Amy L. Chamberlain, Ya-Chen Chang, Mingzhong Chen, Peifeng Chen, Jonathan M. Cooper, Colleen Fridley, Mridul Ghosh, Deepika Gollapudi, Janel Holland-Linn, Joe Horwitz, Althaf I. Hussain, Vera B. Ivleva, Florence Kaltovich, Kristin Leach, Christopher Lee, Amy Liu, Xun Liu, Slobodanka D. Manceva, Amritha Menon, Attila Nagy, Sarah O’Connell, Rahul Ragunathan, Jennifer Walters, Zhong Zhao

2021The Lancet Respiratory Medicine67 citationsDOIOpen Access PDF

Topics & Concepts

MedicineImmunogenicityTolerabilityVirologyAdverse effectInternal medicineImmunologyAntibodyRespiratory viral infections researchVirus-based gene therapy researchCOVID-19 Clinical Research Studies
Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial | Litcius