Electrochemical electrophilic bromination/spirocyclization of <i>N</i>-benzyl-acrylamides to brominated 2-azaspiro[4.5]decanes
Zhongyi Zhang, Zhong‐Wei Hou, Hao Chen, Pinhua Li, Lei Wang
Abstract
An electrochemical electrophilic bromination/spirocyclization of N -benzyl-acrylamides to brominated 2-azaspiro[4.5]decanes with 2-bromoethan-1-ol as the brominating reagent has been developed.
Topics & Concepts
HalogenationElectrophileChemistryElectrochemistryCombinatorial chemistryOrganic chemistryMedicinal chemistryCatalysisElectrodePhysical chemistryOxidative Organic Chemistry ReactionsVanadium and Halogenation ChemistryRadical Photochemical Reactions