Litcius/Paper detail

A meta‐analysis of human papillomavirus prevalence and types among Iranian women with normal cervical cytology, premalignant lesions, and cervical cancer

Zahra Salavatiha, Mohammad Farahmand, Zabihollah Shoja, Somayeh Jalilvand

2021Journal of Medical Virology33 citationsDOI

Abstract

In this study, all data from Iran on human papillomavirus (HPV) prevalence and types among women with normal cervical cytology, premalignant lesions, and cervical cancer were obtained and pooled. The overall HPV prevalence was found to be 9% in women with a normal cervix, 55% in atypical squamous cells of undetermined significance or atypia cases, 58% and 69% in women with low and high grade squamous intraepithelial lesions, respectively, and 81% among women with invasive cervical cancer. In all of the studied groups, HPV 16 was the most common HPV type, followed by HPV 18. In conclusion, this meta-analysis revealed that it will be beneficial if current HPV vaccines are integrated into the national vaccination programs of Iran.

Topics & Concepts

MedicineCervical cancerCytologyHuman papillomavirusCervixCervical intraepithelial neoplasiaAtypiaGynecologyKoilocyteHPV infectionCancerInternal medicinePathologyCervical Cancer and HPV ResearchGenital Health and DiseaseHepatitis B Virus Studies