Programmed cell death 10 increased blood-brain barrier permeability through HMGB1/TLR4 mediated downregulation of endothelial ZO-1 in glioblastoma
Sisi Wu, Junwen Wang, Jingdian Liu, Hongtao Zhu, Ran Li, Xueyan Wan, Jin Lei, Yu Li, Chaoqun You, Feng Hu, Suojun Zhang, Kai Zhao, Kai Shu, Ting Lei
Topics & Concepts
Downregulation and upregulationBlood–brain barrierEndothelial stem cellVascular permeabilityTight junctionHMGB1TLR4Cancer researchParacrine signallingCell biologyChemistryIn vitroBiologyMedicineSignal transductionPathologyReceptorInternal medicineBiochemistryGeneCentral nervous systemBarrier Structure and Function StudiesFerroptosis and cancer prognosisNeuroinflammation and Neurodegeneration Mechanisms