Long non-coding RNA DPP10-AS1 exerts anti-tumor effects on colon cancer via the upregulation of ADCY1 by regulating microRNA-127-3p
Gang Liu, Hui Zhao, Qiang Song, Guangmeng Li, Shuying Lin, Sheng Xiong
Abstract
assays. Taken together, this study demonstrates that DPP10-AS1 inhibits CCSC proliferation by regulating miR-127-3p and ADCY1, providing fresh insight into a promising novel treatment strategy for colon cancer.
Topics & Concepts
Downregulation and upregulationCancer researchBiologymicroRNAMetastasisApoptosisCell biologyCancerGeneticsGeneCancer-related molecular mechanisms researchRNA modifications and cancerMicroRNA in disease regulation