Litcius/Paper detail

Therapeutic role of taurine as antioxidant in reducing hypertension risks in rats

Marwan A. Ibrahim, Mostafa M. Eraqi, Faiz Abdulaziz Alfaiz

2020Heliyon27 citationsDOIOpen Access PDF

Abstract

AIM: The current investigation focused on the therapeutic role of the administration of taurine on hypertensive rats to reduce or cure the hazard effects of hypertension problems. METHODOLOGY: experiment, it contains normal control rats', hypertensive rats were served as hypertension recovery group and hypertensive rats were took orally by the help of gastric tube 50 mg taurine/100 g b.wt/day for four weeks and served as taurine group. RESULTS: experimental taurine significantly reduced the BP as compared with hypertensive control. Furthermore, a significant improvement occurred in the mean value of most investigation parameters in hypertensive animal group which treated with taurine. CONCLUSION: The previous data could be concluded that, there is an obvious amelioration effects of taurine on hypertensive rats by reducing the hazard effects of hypertension problems. The primary mechanisms were discussed according to existing published investigations.

Topics & Concepts

TaurineAntioxidantMedicinePharmacologyInternal medicineTraditional medicineChemistryBiochemistryAmino acidAldose Reductase and TaurinePeroxisome Proliferator-Activated ReceptorsNatural Antidiabetic Agents Studies