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Unraveling the plasma dynamics, oxidative metabolism and excretion behavior of M-PEG6-OH by UPLC-MS/MS

Yingxia Guo, Jiaxin Zhang, R.D. van der Mei, Zihan Tang, Meichen Liu, Xixian Weng, Meiyun Shi, Lei Yin

2025Journal of Pharmaceutical and Biomedical Analysis6 citationsDOI

Topics & Concepts

ChemistryExcretionPharmacokineticsMetabolitePEG ratioHigh-performance liquid chromatographyUrineChromatographyPEGylationLiquid chromatography–mass spectrometryBiotransformationMetabolismBiodistributionPolyethylene glycolPharmacologyBiochemistryMass spectrometryEnzymeIn vitroMedicineEconomicsFinanceNanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsPharmacological Effects and Toxicity Studies
Unraveling the plasma dynamics, oxidative metabolism and excretion behavior of M-PEG6-OH by UPLC-MS/MS | Litcius